Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 14 Researches
8.1
USERS' SCORE
Good
Based on 21 Reviews
8
Supplement Facts
Serving Size:  1 Veggie Capsule
Amount Per Serving
%DV
Vitamin C (as ascorbic acid)
40 mg
44%
Thiamin (as thiamin HCl)
60 mg
5000%
Riboflavin (as riboflavin and riboflavin-5-phosphate)
75 mg
5769%
Niacin (as niacinamide and niacin)
50 mg
313%
Vitamin B6 (from pyridoxine HCl and pyridoxal-5-phosphate)
50 mg
2941%
Folate (as (6S)-5-methyltetrahydrofolic acid, glucosamine salt) (Quatrefolic®)
400 mcg DFE
100%
Vitamin B12 (as methylcobalamin)
1000 mcg
41677%
Biotin
600 mcg
2000%
Pantothenic Acid (as d-calcium pantothenate)
100 mg
2000%

Top Medical Research Studies

9
Vitamin B12 effectively reduces pain
We sought to understand how intramuscular vitamin B12 could help alleviate low back pain in patients with mechanical lumbago. In a rigorous study involving 60 participants, we compared the effects of vitamin B12 to a placebo.

Our findings indicated that those receiving the vitamin reported significantly less pain and disability, as measured by a visual scale and disability questionnaire. Notably, those on vitamin B12 also used less paracetamol than the placebo group.

Overall, our study confirmed that vitamin B12 can be effective for treating low back pain without nutritional deficiency.
Read More
8
Methylcobalamin shows promising effectiveness
This study evaluated the effects of intramuscular methylcobalamin injections on chronic low back pain.

In a rigorously designed double-blinded, randomized controlled trial, 60 patients were divided into treatment and placebo groups.

We observed significant improvements in pain and disability scores among those receiving methylcobalamin compared to the placebo.

Additionally, the treatment was found to be safe, with only minor side effects reported.
Read More
8
Vitamin B complex aids back pain relief
We examined how well celecoxib and a combined vitamin B complex worked for people experiencing lower back pain, comparing them with meloxicam.

Our findings indicated that celecoxib, especially when paired with Neuromultivit (a vitamin B complex), showed improved effectiveness in relieving both acute and chronic back pain.

Interestingly, while meloxicam offered similar initial pain relief, celecoxib was found to be superior for long-term recovery and quality of life improvements.

This suggests that adding vitamin B to treatment could enhance outcomes for those suffering from chronic lower back pain.
Read More

Most Useful Reviews

9
Alleviated numbness
7 people found this helpful
I gave this to my mother, who suffered from hand pain and numbness due to a nerve issue. After taking the product, she experienced considerable relief from the numbness.
Read More
9
Disappeared back pain
6 people found this helpful
Excellent product! I had persistent back pain that has now disappeared. The pill size is slightly bothersome, but the quality is superb, and it's packed with ingredients that aid absorption.
Read More
9
Back pain relief
5 people found this helpful
The best B-complex vitamins I've tried! A neurologist recommended them for my osteochondrosis, and I've found remarkable relief from back pain. They are now a staple in my first-aid kit.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 14 Researches
8.1
  • All Researches
9
Combination therapy shows effectiveness
We set out to explore whether a rehabilitation program combined with specific supplements could effectively treat sciatica in young patients. Our study involved 128 individuals who were divided into three groups: one receiving both rehabilitation and supplements, one only with rehabilitation, and one with only supplements.

After treatment, the group with both rehabilitation and supplements showed significant improvement in pain relief and overall quality of life compared to the others. While the supplement-only group didn’t perform as well, this combination approach proved beneficial, particularly in reducing pain and enhancing stability.
Read More
We explored how effective vitamin B complex, alongside nonsteroidal anti-inflammatory drugs, is in treating back pain. Our study involved 70 patients divided into two groups, one receiving a vitamin B complex blend and the other a different pain relief combination.

Both groups showed improvement, but the first group experienced a clearer reduction in pain levels over time. By the third visit, they reported significantly less discomfort compared to the second group. Though both treatments were effective, the vitamin B complex showed a more pronounced impact on pain relief and patient satisfaction.
Read More
9
Vitamin B12 effectively reduces pain
We sought to understand how intramuscular vitamin B12 could help alleviate low back pain in patients with mechanical lumbago. In a rigorous study involving 60 participants, we compared the effects of vitamin B12 to a placebo.

Our findings indicated that those receiving the vitamin reported significantly less pain and disability, as measured by a visual scale and disability questionnaire. Notably, those on vitamin B12 also used less paracetamol than the placebo group.

Overall, our study confirmed that vitamin B12 can be effective for treating low back pain without nutritional deficiency.
Read More
9
Vitamin B complex effective for pain
We examined how Dolo-Neurobion, a blend of essential B vitamins and an analgesic, affects acute lumbosacral pain. In a study of 53 patients, we found that this treatment yielded good to excellent results in 77.4% of cases, while 15.1% experienced moderate effects. The approach combined initial parenteral dosing with continuation through oral intake, and any necessary antibiotics were also used. Most notably, we observed no significant side effects, making Dolo-Neurobion a promising option for back pain relief linked to pelvic organ issues.
Read More
8
Vitamin B12 aids postoperative recovery
We explored how combining dexamethasone with vitamin B12 could impact early recovery from back and leg pain after a specific spine surgery called percutaneous endoscopic interlaminar discectomy (PEID).

In our study, patients were divided into two groups: one received only the surgery, while the other got epidural injections of both medications during surgery.

Results showed that the combined treatment significantly reduced pain and inflammation, leading to better early recovery outcomes. This suggests that using this combination might be a great option for patients undergoing this type of surgery.
Read More

User Reviews

USERS' SCORE
Good
Based on 21 Reviews
8
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Alleviated numbness
7 people found this helpful
I gave this to my mother, who suffered from hand pain and numbness due to a nerve issue. After taking the product, she experienced considerable relief from the numbness.
Read More
9
Disappeared back pain
6 people found this helpful
Excellent product! I had persistent back pain that has now disappeared. The pill size is slightly bothersome, but the quality is superb, and it's packed with ingredients that aid absorption.
Read More
9
Back pain relief
5 people found this helpful
The best B-complex vitamins I've tried! A neurologist recommended them for my osteochondrosis, and I've found remarkable relief from back pain. They are now a staple in my first-aid kit.
Read More
7.5
Less knee pain
5 people found this helpful
Prescribed for my knee joint pain, this remedy has brought much-needed relief. After consistent use and a proper diet, my knee pain has decreased, making my legs more resilient for activity.
Read More
9
Effective for back pain
1 people found this helpful
These B vitamins are effective for my back pain, numbness, and poor sleep. I’ve noticed the symptoms return when I stop taking them. This product has positively influenced my well-being, and I will be reordering it.
Read More

Frequently Asked Questions

9
Less joint pain
I’ve been using this for years. There's a noticeable difference in my overall condition regarding back pain; I experience much less discomfort when I take it compared to when I don’t. I appreciate its ingredients.
9
Alleviated numbness
7 people found this helpful
I gave this to my mother, who suffered from hand pain and numbness due to a nerve issue. After taking the product, she experienced considerable relief from the numbness.
9
Disappeared back pain
6 people found this helpful
Excellent product! I had persistent back pain that has now disappeared. The pill size is slightly bothersome, but the quality is superb, and it's packed with ingredients that aid absorption.
9
Back pain relief
5 people found this helpful
The best B-complex vitamins I've tried! A neurologist recommended them for my osteochondrosis, and I've found remarkable relief from back pain. They are now a staple in my first-aid kit.
9
Effective for back pain
1 people found this helpful
These B vitamins are effective for my back pain, numbness, and poor sleep. I’ve noticed the symptoms return when I stop taking them. This product has positively influenced my well-being, and I will be reordering it.
9
No back pain
1 people found this helpful
This dietary supplement has greatly improved my condition. A week before my critical days, I typically suffer from lower back pain and extreme fatigue. However, I felt almost normal, with renewed energy and no pain. I highly recommend it.
7.5
Less knee pain
5 people found this helpful
Prescribed for my knee joint pain, this remedy has brought much-needed relief. After consistent use and a proper diet, my knee pain has decreased, making my legs more resilient for activity.
7.5
Reduced back pain
13 people found this helpful
I suffered from severe back pain and stiffness, with no effect from acupuncture. Suspecting a vitamin B deficiency, I started taking supplements, and my back pain has considerably improved. I plan to continue this and possibly try a multi-vitamin. This product is excellent, and I noticed no unpleasant odour from the vitamin B.
7.5
Relieved knee pain
1 people found this helpful
After taking the supplement for a few weeks, I experienced knee pain that vanished, showing improvement. I adjusted my dosage to two pills a day, which seems to help.
8
Vitamin B Complex enhances pain relief
We conducted a thorough multicenter study involving 418 patients to assess the combined effect of diclofenac and vitamin B1, B6, and B12 on back pain. Over two weeks, we found that more patients achieved complete pain relief with the vitamin combination compared to diclofenac alone.

Specifically, 53 patients on the combination ended treatment early due to sufficient relief, compared to 48 in the diclofenac-only group. The results also showed significant improvements in pain scores, especially for those with severe pain. While some side effects were noted, they were similar between both treatment groups.
8
Vitamin B complex aids back pain relief
We examined how well celecoxib and a combined vitamin B complex worked for people experiencing lower back pain, comparing them with meloxicam.

Our findings indicated that celecoxib, especially when paired with Neuromultivit (a vitamin B complex), showed improved effectiveness in relieving both acute and chronic back pain.

Interestingly, while meloxicam offered similar initial pain relief, celecoxib was found to be superior for long-term recovery and quality of life improvements.

This suggests that adding vitamin B to treatment could enhance outcomes for those suffering from chronic lower back pain.
We analyzed a study that looked at how B vitamins—B1, B6, and B12—work alongside diclofenac to help relieve back pain in people suffering from acute lumbago.

In a randomized, double-blind trial, participants received either diclofenac plus B vitamins or diclofenac alone. After three days, those taking the combination therapy reported significantly better pain relief and mobility than those on diclofenac only.

Despite the encouraging results, we noted that the study recorded pain measurements only until participants withdrew, which could impact the findings.

References

  1. He C, Li J, Hu W, Xiao B, Fan T, et al. Effects of dexamethasone combined with vitamin B12 on percutaneous endoscopic interlaminar discectomy early outcomes: a randomized controlled trial. J Orthop Surg Res. 2024;19:733. doi:10.1186/s13018-024-05210-z
  2. Scaturro D, Vitagliani F, Tomasello S, Sconza C, Respizzi S, et al. Combined Rehabilitation with Alpha Lipoic Acid, Acetyl-L-Carnitine, Resveratrol, and Cholecalciferolin Discogenic Sciatica in Young People: A Randomized Clinical Trial. Medicina (Kaunas). 2023;59. doi:10.3390/medicina59122197
  3. Antonen EG, Kruchek MM, Nikitina MV. [Evaluation of the effectiveness of treatment of patients with nonspecific pain syndrome in the lower back with celecoxib and a combined preparation of B vitamins]. Zh Nevrol Psikhiatr Im S S Korsakova. 2022;122:65. doi:10.17116/jnevro202212208165
  4. Barantsevich ER, Yakovlev AA, Gavrilova EA, Gavrichenko AV, Pushkarev MS, et al. [Study of the clinical efficacy and safety of the scheme of step therapy of nonsteroidal anti-inflammatory drugs and a complex of B vitamins in patients with low back pain]. Zh Nevrol Psikhiatr Im S S Korsakova. 2021;121:67. doi:10.17116/jnevro202112110167
  5. Nava-Mesa MO, Aispuru Lanche GR. [Role of B vitamins, thiamine, pyridoxine, and cyanocobalamin in back pain and other musculoskeletal conditions: a narrative review]. Semergen. 2021;47:551. doi:10.1016/j.semerg.2021.01.010
  6. Calderon-Ospina CA, Nava-Mesa MO, Arbeláez Ariza CE. Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis. Pain Med. 2020;21:766. doi:10.1093/pm/pnz216
  7. Khabirov FA, Khaibullin TI, Granatov EV. [Evaluation of efficiency and safety of adding neuromultivit to basic therapy of vertebrogenic radiculopathy]. Zh Nevrol Psikhiatr Im S S Korsakova. 2017;117:38. doi:10.17116/jnevro201711710138-43
  8. Chiu CK, Low TH, Tey YS, Singh VA, Shong HK. The efficacy and safety of intramuscular injections of methylcobalamin in patients with chronic nonspecific low back pain: a randomised controlled trial. Singapore Med J. 2011;52:868.
  9. Levin OS, Moseĭkin IA. [Vitamin B complex (milgamma) in the treatment of vertebrogenic lumbosacral radiculopathy]. Zh Nevrol Psikhiatr Im S S Korsakova. 2009;109:30.
  10. Mibielli MA, Geller M, Cohen JC, Goldberg SG, Cohen MT, et al. Diclofenac plus B vitamins versus diclofenac monotherapy in lumbago: the DOLOR study. Curr Med Res Opin. 2009;25:2589. doi:10.3111/13696990903246911
  11. Mauro GL, Martorana U, Cataldo P, Brancato G, Letizia G. Vitamin B12 in low back pain: a randomised, double-blind, placebo-controlled study. Eur Rev Med Pharmacol Sci. 2000;4:53.
  12. Brüggemann G, Koehler CO, Koch EM. [Results of a double-blind study of diclofenac + vitamin B1, B6, B12 versus diclofenac in patients with acute pain of the lumbar vertebrae. A multicenter study]. Klin Wochenschr. 1990;68:116.
  13. Kuhlwein A, Meyer HJ, Koehler CO. [Reduced diclofenac administration by B vitamins: results of a randomized double-blind study with reduced daily doses of diclofenac (75 mg diclofenac versus 75 mg diclofenac plus B vitamins) in acute lumbar vertebral syndromes]. Klin Wochenschr. 1990;68:107.
  14. Kunt T. [Complaints in the lumbosacral region and their management with Dolo-Neurobion]. Fortschr Med. 1978;96:299.
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